In the good pilot investigation, Sullivan and you will associates (2013) examined the application of endoscopic ambition therapy for the treatment of carrying excess fat

In the good pilot investigation, Sullivan and you will associates (2013) examined the application of endoscopic ambition therapy for the treatment of carrying excess fat

AspireAssist Aspiration Therapy

This method entails endoscopic placement of a gastrostomy tube (A-Tube) and the AspireAssist siphon assembly (Aspire Bariatrics, King of Prussia, PA) to aspirate gastric contents 20 minutes after meal consumption. These researchers performed a study of 18 obese subjects who were randomly assigned (2:1) to groups that underwent aspiration therapy for 1 year plus lifestyle therapy (n = 11; mean BMI, 42.6 ± 1.4 kg/m(2)) or lifestyle therapy only (n = 7; mean BMI, 43.4 ± 2.0 kg/m(2)). Lifestyle intervention comprised a 15-session diet and behavioral education program; 10 of the 11 subjects who underwent aspiration therapy and 4 of the 7 subjects who underwent lifestyle therapy completed the 1st year of the study. After 1 year, subjects in the aspiration therapy group lost 18.6 % ± 2.3 % of their body weight (49.0 % ± 7.7 % of EWL) and those in the lifestyle therapy group lost 5.9 % ± 5.0 % (14.9 % ± 12.2 % of EWL) (p < 0.04); 7 of the 10 subjects in the aspiration therapy group completed an additional year of therapy and maintained a 20.1 % ± 3.5 % body weight loss (54.6 % ± 12.0 % of EWL). There were no AEs of aspiration therapy on eating behavior and no evidence of compensation for aspirated calories with increased food intake. No episodes of binge eating in the aspiration therapy group or serious AEs were reported. The authors concluded that aspiration therapy appeared to be a safe and effective long-term weight loss therapy for obesity. These preliminary findings from a pilot study need to be validated by well-designed studies.

Forssell and you will Noren (2015) evaluated the effectiveness of a manuscript equipment, brand new AspireAssist aspiration cures system, for treating being obese. Immediately following 4 weeks providing a highly-low-fat diet, twenty five overweight group (Bmi 39.8 ± 0.9 kg/m(2)) had the AspireAssist gastrostomy tube set while in the an effective gastroscopy. A low-character device are installed two weeks later and you will aspiration of gastric articles try did up to twenty minutes after items 3 times for each day. Cognitive behavioural treatment has also been started. Within few days 6, indicate lbs missing was 16.5 ± seven.8 kg on 22 sufferers who done 26 months out of procedures (p = 0.001). New imply payment EWL was forty.8 ± 19.8 % (p = 0.001); 2 sufferers was basically hospitalized for issue: step one subject to possess aches immediately following gastrostomy tube positioning, which had been given analgesics, plus one because of an enthusiastic aseptic intra-intestinal liquid collection day just after gastrostomy tubing positioning. Zero clinically tall alterations in serum potassium and other electrolytes taken place. The new people figured in this study, reasonable diet is hit that have pair complications utilizing the AspireAssist program, recommending its likely once the an attractive therapeutic equipment to own heavy people.

Efficient ambition required comprehensive chewing of drank restaurants

In a prospective observational study, Noren and Forssell (2016) evaluated the safety and effectiveness of the novel AspireAssist Aspiration Therapy System for treatment of obesity, and its effect on patient’s quality of life. A total of 25 obese subjects, mean age of 48 years (range of 33 to 65) were included in this study. A custom gastrostomy tube (A-tube) was percutaneously inserted during a gastroscopy performed under conscious sedation. Drainage and mate1 irrigation of the stomach were performed 3 times daily, 20 mins after each meal, for 1 to 2 years. Treatment included a cognitive behavioral weight loss program. Mean BMI at inclusion was 39.8 kg/m2 (range of 35 to 49). After 1 year mean (SD) BMI was 32.1 kg/m2 (5.4), p < 0.01, and EWL was 54.4 % (28.8), p < 0.01. Quality of life, as measured with EQ-5D, improved from 0.73 (0.27) to 0.88 (0.13), p < 0.01. After 2 years BMI was 31.0 kg/m2 (5.1), p < 0.01, and EWL was 61.5 % (28.5), p < 0.01. There were no serious AEs or electrolyte disorderspliance was 80 % after 1 year and 60 % after 2 years. The authors concluded that aspiration therapy is a safe and efficient treatment for obesity, and weight reduction improves quality of life. Excess weight was approximately halved in a year, with weight stability if treatment was continued; and long-term results remain to be investigated.

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